The twelfth time Sheol is mentioned in the Bible is in Job 7:9. Chapter 7 is one of the most anguishing parts of Job's discourse, as he pointedly questions the persistent trials he suffered.
As usual, translating from Hebrew, we get:
"The cloud fades - vanishes - so he who goes down to Sheol shall not come up." - Job 7:9
The KJV renders it this way: "As the cloud is consumed and vanisheth away: so he that goeth down to the grave shall come up no more."
This compares the person who goes to Sheol to a fading, vanishing cloud. It is an apt description, since our bodies dissolve and turn to "dust" after death.
Here, like we've seen so far, Sheol clearly means the grave.